![]() Our study shows the feasibility of continuous, objective, sensitive, and passive assessment of PD at home and hence has the potential of improving clinical care and drug clinical trials.Īuthor contributions: Conceptualization: Y.L., G.Z., C.G.T., T.E., E.R.D., and D.K. Further, the monitored gait speed was able to capture symptom fluctuations in response to medications and their impact on patients’ daily functioning. ![]() At-home gait speed also provides a more sensitive marker for tracking disease progression over time than the widely used MDS-UPDRS. Cross-sectional analysis of the data shows that at-home gait speed strongly correlates with gold-standard PD assessments, as evaluated by the Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) part III subscore and total score. We collected over 200,000 gait speed measurements. We continuously monitored 50 participants, with and without PD, in their homes for up to 1 year. ![]() The device detected and analyzed the radio waves that bounce off people’s bodies and inferred their movements and gait speed. We used a radio device located in the background of the home. In this work, we demonstrate an effective approach for assessing PD severity, progression, and medication response at home, in an objective manner. ![]() Existing methods are semisubjective and require visiting the clinic. A key challenge in PD is tracking disease severity, progression, and medication response. Parkinson’s disease (PD) is the fastest-growing neurological disease in the world. ![]()
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